In Honor of My Mother, International Women’s Day and the #MeToo Movement
by Jacques Fleury
[From Fleury’s Boston Globe featured book Sparks in the Dark: A Lighter Shade of Blue, A Poetic Memoir]
Through my senses, I see sadly her unaffected gazes Her intrigue’s absences Her relationship to relationships Slowly and softly bending Like two birds sharing a stem The thin branch softly bending Sighs with her burden; Trapped in discontentment Like Winter’s malevolence, But she found in her a weather of resilience, The sounds of her heels on the stoical pavement echoes like
her laughter in the desert paths of remembrance She throws her head back and laughs As young men beg for a chance to kill her lack of chance Her essence glowing like the moon in starless skies She like a picturesque whirl like a slow-moving storm, Slowly rushes into a room Smiles in recognition of her adulation Then sways her hips ever so lovingly Among the artful debris And cocks her head as if to hear the dead Extending her left ear to face the light Oblivious to the presence of a challenge Waiting to hear words to confirm her rights And a tear from the moon falls into her eyes Then in her benediction glows Then in her benediction grows So she opens her mouth and blows a hue of winter, But sometimes she opens her mouth and blows a hue of summer, Depending on the noisiest weather! One day she opened her eyes in horror To see the moon a reddish color! To see her world of beauty in fury crumbling around her like a fallen deity So then she crumbles too; Having been made of snow, The wrath of the wind broke through her window, then there she lies like the ashes of winter, succumbed to the intemperate weather, Then I watch her die, beautifully die.
Jacques Fleury
Jacques Fleury is a Boston Globe featured Haitian American Poet, Educator, Author of four books and literary arts student at Harvard University online. His latest publication “You Are Enough: The Journey to Accepting Your Authentic Self” & other titles are available at all Boston Public Libraries, the University of Massachusetts Healey Library, University of Wyoming, Askews and Holts Library Services in the United Kingdom, The Harvard Book Store, The Grolier Poetry Bookshop, Amazon etc… He has been published in prestigious publications such as Spirit of Change Magazine, Wilderness House Literary Review, Muddy River Poetry Review, Litterateur Redefining World anthologies out of India, Poets Reading the News, the Cornell University Press anthology Class Lives: Stories from Our Economic Divide, Boston Area Small Press and Poetry Scene among others…Visit him at: http://www.authorsden.com/jacquesfleury.–
Jacques Fleury’s book You Are Enough: The Journey Towards Understanding Your Authentic Self
DETECTION OF DISEASES THROUGH THE ANALYSIS OF RED AND WHITE BLOOD CELLS, HEMOGLOBIN, AND OTHER COMPONENTS IN BLOOD AND LABORATORY DIAGNOSTICS
Jorakulova Gulshoda Uchqun qizi
3rd-year student, Faculty of Medical Biology
Bukhara State Medical Institute named after Abu Ali ibn Sina
E-mail:gulshodajoraqulova819@gmail.com
Abstract:
This article highlights the possibilities of identifying various diseases in the human body through laboratory analysis of blood composition. In particular, the diagnostic significance of red blood cells, white blood cells-leukocytes, hemoglobin, platelets, and other biochemical indicators is thoroughly analyzed. The article substantiates that blood tests enable early detection of anemia, infectious diseases, inflammatory processes, immune system disorders, and functional changes in internal organs. Furthermore, the role of laboratory diagnostics in modern medicine, as well as its importance in disease prevention and improving treatment effectiveness, is discussed. This topic plays a crucial role in early disease detection, maintaining public health, and strengthening preventive measures.
Keywords:
Blood analysis, erythrocytes, leukocytes, hemoglobin, platelets, laboratory diagnostics, anemia, infection, inflammation, immune system, biochemical analysis, early disease detection, medical examination, body condition.
INTRODUCTION:
Blood is a vital biological fluid in the human body that performs essential life-sustaining functions. It plays a key role in delivering oxygen and nutrients to tissues, removing metabolic waste products, and ensuring immune protection. Therefore, changes in blood composition provide important information about physiological and pathological processes occurring in the body.
In modern medicine, laboratory diagnostics is considered one of the most reliable and rapid methods for disease detection. Blood tests, in particular, allow early diagnosis of diseases, assessment of their progression, and monitoring of treatment effectiveness. The components of blood, including erythrocytes, leukocytes, hemoglobin, platelets, and various biochemical indicators, serve as important markers of human health.
Today, many diseases such as infectious diseases, cardiovascular disorders, anemia, diabetes mellitus, and others are widespread, making early detection a pressing issue. Laboratory blood analysis plays a crucial role in identifying these conditions at an early stage and preventing complications.
Moreover, advances in laboratory diagnostics have improved analytical methods, enabling more accurate and rapid results. This greatly assists physicians in making correct diagnoses and determining effective treatment strategies.
The aim of this article is to study the possibilities of disease detection through the analysis of key blood indicators such as erythrocytes, leukocytes, hemoglobin, and others, and to highlight the importance of laboratory diagnostics in medicine.
MAIN PART:
1. Erythrocytes and Their Diagnostic Significance
Erythrocytes are one of the main cellular components of blood, responsible for transporting oxygen from the lungs to tissues and carbon dioxide from tissues to the lungs. Their quantity and quality are important indicators in assessing the general condition of the body.
A decrease in erythrocyte count may be associated with anemia, blood loss, iron deficiency, vitamin B12 deficiency, or impaired bone marrow function. Conversely, an increase in erythrocyte count may occur due to dehydration, heart and lung diseases, or adaptation to high-altitude conditions. Therefore, erythrocyte levels help evaluate oxygen exchange and detect disorders of the hematological system.
2. Hemoglobin and Its Importance
Hemoglobin is an iron-containing protein within erythrocytes that is responsible for oxygen transport. It reflects the level of oxygen supply in the body.
A decrease in hemoglobin levels is commonly associated with iron deficiency anemia, chronic diseases, or poor nutrition. Symptoms may include fatigue, dizziness, and weakness. Elevated hemoglobin levels may indicate blood thickening, dehydration, or hypoxia (oxygen deficiency). Thus, hemoglobin is a key parameter in clinical diagnosis.
3. Leukocytes and the Immune System
Leukocytes are the primary cells responsible for protecting the body against infections and foreign agents. They are an essential part of the immune system.
An increase in leukocyte count (leukocytosis) is usually observed in bacterial infections, inflammatory processes, injuries, or stress. A decrease (leukopenia) may indicate viral infections, weakened immunity, or bone marrow dysfunction. Differential analysis of leukocyte subtypes (such as neutrophils and lymphocytes) helps determine the type and cause of disease.
4. Platelets and the Blood Clotting System
Platelets are blood components that play a crucial role in clotting. They are produced in the bone marrow and are responsible for stopping bleeding and repairing damaged blood vessels.
When a vessel is injured, platelets adhere to the site and form a clot, releasing biologically active substances that activate clotting mechanisms.
A decrease in platelet count may occur in viral infections, as a result of certain medications, bone marrow suppression, or autoimmune diseases. Symptoms include nosebleeds, hematomas and gum bleeding.
An increase in platelet count may be associated with inflammatory diseases, tumors, or postoperative conditions. This increases the risk of excessive clotting and thrombosis. Therefore, platelet count and function are essential for evaluating the clotting system.
5. Erythrocyte Sedimentation Rate
The erythrocyte sedimentation rate is an important laboratory indicator that measures how quickly erythrocytes settle in plasma over time. It indirectly reflects the presence of inflammation or pathological processes.
Under normal conditions, erythrocytes settle slowly. However, during inflammation, plasma proteins such as fibrinogen increase, promoting aggregation of erythrocytes and accelerating their sedimentation.
Elevated ESR is observed in bacterial and viral infections, chronic inflammatory diseases, autoimmune disorders, and oncological processes. It may also slightly increase in physiological conditions such as pregnancy.
Decreased ESR is less common and may be associated with increased blood viscosity or elevated erythrocyte count. Although ESR does not provide a specific diagnosis, it serves as an important indicator of underlying disease and is interpreted alongside other tests.
6. Biochemical Blood Analysis
Biochemical blood analysis is widely used to assess the function of internal organs, including the liver, kidneys, and pancreas.
For example:
Glucose level is used to diagnose diabetes mellitus
Creatinine and urea assess kidney function
ALT and AST evaluate liver function
These indicators help detect even latent diseases.
Creatinine and urea are key markers of kidney function, and their elevation may indicate renal failure.
ALT and AST indicate liver cell damage and are elevated in hepatitis, cirrhosis, or toxic injury.
Bilirubin is important in assessing liver and bile duct function, and its increase leads to jaundice.
Cholesterol and lipids play a key role in evaluating cardiovascular disease risk.
Additionally, biochemical analysis allows detection of subclinical conditions and monitoring of disease progression and treatment effectiveness. Therefore, it is one of the most important and widely used diagnostic tools in modern medicine.
7. Role of Blood Tests in Early Disease Detection
Blood tests are among the most effective and convenient methods for early disease detection. Many diseases do not present clear clinical symptoms in their initial stages, but changes occur in blood composition.
For example:
Decreased hemoglobin and erythrocytes indicate anemia
Changes in leukocytes indicate infections
Glucose levels reveal diabetes
Biochemical parameters indicate liver and kidney diseases
Blood tests are also important for preventive purposes. Regular examinations in healthy individuals help detect latent diseases and prevent their progression.
During treatment, blood tests are used to:
Evaluate treatment effectiveness
Monitor drug effects
Track disease progression
Early diagnosis simplifies treatment, reduces costs, and prevents serious complications.
8. Modern Importance of Laboratory Diagnostics
Laboratory diagnostics is an integral part of modern medicine, playing a key role in disease detection, evaluation, and treatment monitoring.
Advances in science and technology have significantly improved the accuracy, speed, and reliability of laboratory tests. Automated analyzers allow rapid processing of multiple parameters while minimizing human error.
It also plays a major role in personalized medicine, where treatment is tailored based on individual patient characteristics. Modern immunological, molecular-genetic, and biochemical tests enable the detection of complex diseases.
Overall, laboratory diagnostics significantly improves healthcare quality and patient outcomes.
CONCLUSION:
Laboratory analysis of blood composition is one of the most important and reliable methods for detecting physiological and pathological processes in the human body. Blood components such as erythrocytes, leukocytes, hemoglobin, platelets, and biochemical indicators provide valuable information for assessing overall health, evaluating internal organ function, and diagnosing various diseases.
Changes in these indicators enable early detection of anemia, infectious diseases, inflammatory processes, immune disorders, and cardiovascular and internal organ diseases. This facilitates timely treatment and reduces the risk of complications.
Moreover, advances in laboratory diagnostics have improved the accuracy and speed of analysis, assisting physicians in making accurate diagnoses and implementing effective treatments.
In conclusion, blood tests are indispensable in maintaining human health, enabling early disease detection, and ensuring effective treatment, making them an essential part of modern medicine.
Laboratory analysis of blood is one of the most reliable diagnostic methods. It provides essential information about health status and helps detect diseases at early stages. Advances in laboratory diagnostics have improved accuracy and efficiency, making it indispensable in modern medicine.
REFERENCES:
1-Abbas AK, Lichtman AH, Pillai S. Cellular and Molecular Immunology. Elsevier; 2021.
2-Hall JE. Guyton and Hall Textbook of Medical Physiology. Elsevier; 2020.
3-McPherson RA, Pincus MR. Henry’s Clinical Diagnosis and Management by Laboratory Methods. Elsevier; 2021.
Living is the breaking of one boundary after another.
Life grows colder as it goes on.
The time they wrote
abandons them in the end.
On a spring day when cherry blossoms befriend the wind,
mountain-like buildings,
valley-like alleys,
water-like people.
People, worn by strangeness,
save it sparingly, fearing they might grow used to it.
An angel slips between their lips,
and they take out a single smile.
한 마디 말처럼
하늘과 땅은 영원의 입술
거기,
한 마디 말처럼 우리는 산다
누구의 손에 끼웠는지
모르고 사는 반지처럼
세상에 끼워 사는 사람들
오늘은
어디 있는지 몰라
그냥 서 있는 곳
손으론 손자국 판화
발로는 발자국 판화
삶은 허공에서 길 찿기
새들은 안다
허공이 영원이라는 걸
사는 건 경계가 경계를 허무는 것
목숨은 갈수록 쌀쌀한 남
그들이 쓴 시간이 그들을 버린다
벚꽃이 벗하는 봄날
산 같은 빌딩
계곡 같은 골목
물 같은 사람들
사람들은 낯섦이 닳아
익숙해질까 봐 아껴 쓰고 있다
입에 드나드는 천사
웃음 하나 꺼내 본다
Poet Siyoung Doung graduated from the Department of Korean Language and Literature at Dongguk University and went on to earn a Ph.D. in Korean Language and Literature from Hanyang University. She further expanded her academic pursuits by studying humanities at Regensburg University in Germany. Her teaching career includes positions as a professor at Korea Tourism University and Jilin University of Finance and Economics in China.
Her literary journey began in 2003 with her poetry debut in the literary magazine Dacheung. Since then, she has published numerous poetry collections, including Future Hunting, In Search of a Strange God, The Phone Call from God, The Eyes of November, The Carnival of Time (Anthology), Was It You, Was It Me, or Was It Longing?, The Scent of Secrets, Aria of Everyday Life, The River Flowing Under the Pen, The Magic Letters, and The Horizon Never Gets Wet. In addition to poetry, Doung has contributed significantly to literary research with works such as Roh Cheon-myung’s Poetry and Semiotics, Korean Literature and Semiotics, and Semiotics of Modern Poetry. Her exploration of literature extends into travel writing, with essay collections like Encountering Culture Through Travel and Encountering Travel Through Literature. Her literary excellence has been recognized with numerous prestigious awards, including the Park Hwa-mok Literary Award (2010), Poetry and Poetics Young Poet Award (2011), the Grand Prize at the Korean Buddhist Literature Awards (2018), the 32nd Dongguk Literary Award (2019), the Yeongrang Literary Award for Criticism (2020), and the 7th Woltan Park Jong-hwa Literary Award by the Korean Writers’ Association (2021). Most recently, she received the Literary Youth Work Award in 2024. In recognition of her contributions to literature, She was also a recipient of a creative grant from the Arts Council Korea in 2005.
Amb. Dr. Priyanka Neogi is from Coochbehar. She is an administrative controller of United Nations’ PAF, a librarian, a CEO of Lio Messi International Property & Land Consultancy, international literacy worker, sports & peace promoter, dancer, singer, reciter, live telecaster, writer, editor, researcher, literary journalist, host, beauty queen, international co-ordinator of the Vijay Mission of Community Welfare Foundation of India.
Yet look—half a heart still beats within my chest.
The winds have scattered all my sorrows wide,
How cruelly you have treated love—what a sin.
My aching heart is torn into pieces inside,
Yet look—half a heart still lives within.
They promised love, but all their vows were lies,
They fooled a simple girl with burning dreams.
Only when hearts were wounded did they realize,
Yet look—half a heart remains, it seems.
Do‘sanova Dilnoza Xolmurod qizi was born on June 21, 2006, in Xalqobod, Qiziriq district, Surkhandarya region. She is of Uzbek nationality.
In 2013, she was admitted to the 1st grade of School No. 25 in Qiziriq district, Surkhandarya region. During the 2021–2022 academic years, she studied at a specialized boarding school for in-depth study of selected subjects in Qiziriq district.
In 2024, she graduated from School No. 25 with excellent grades. In the same year, she was admitted as a first-year student to the Faculty of Philology and Language Teaching (Uzbek language, part-time program) at Renaissance Educational University in Tashkent. Currently, she is a second-year student.
Also in 2024, she began working as the head of the Mother Tongue and Literature club at the “Kelajak” center in Qiziriq district, Surkhandarya region. She is a beloved teacher of more than 60 students.
Since 2019, she has been engaged in writing poetry. As a result, she has achieved honorable places in many competitions. The number of her diplomas and national (and international) certificates exceeds 100.